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. 2022 Sep 16;13:957301. doi: 10.3389/fendo.2022.957301

Table 2.

Imaging presentation of the study cohort.

Variable, parameter Unit or category Total Surgical remission Response to first-generation SRLs
Yes No p Good Poor p
N Results N Results N Results N Results N Results
Tumor imaging in MRI, n (%) Microadenoma 146 31 (21.2) 58 23 (40.0) 81 6 (7.4) <0.001 35 5 (14.3) 37 1 (2.7) 0.102
Macroadenoma 115 (78.7) 35 (60.0) 75 (92.6) 30 (85.7) 36 (97.3)
Maximal tumor diameter, Median [IQR] mm 124 19 [12-25] 54 12.5 [9-19] 64 23 [18-30] <0.001 26 22 [16-28] 32 25 [20-35] 0.162
Extrasellar expansion, n (%) yes 129 73 (56.6) 48 14 (29.2) 74 58 (78.4) <0.001 30 18 (60.0) 35 32 [91.4] 0.003
Compression of the optic chiasm, n (%) yes 122 31 (25.4) 48 6 (12.5) 67 25 (37.3) 0.003 28 5 (17.9) 32 19 (59.4) 0.001
Degree of cavernous sinus invasion, n (%) None 130 69 (53.1) 53 44 (83.0) 74 22 (29.7) <0.001 30 12 (40.0) 35 8 (22.9) 0.043
Unilateral 47 (36.2) 9 (17.0) 38 (51.4) 16 (53.3) 17 (48.6)
Bilateral 14 (10.8) 0 (0.0) 14 (18.9) 2 (6.7) 10 (28.6)

The bold values are statistically significant.