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. 2022 Sep 16;13:1004855. doi: 10.3389/fendo.2022.1004855

Table 1.

Baseline characteristics of the MAFLD group and control group.

Variable Total (n=864) Control (n=352) MAFLD (n=512) P-valuea
Gender [n (%)] < 0.001
 Male 624 (72.7) 230 (65.3) 394 (77.0)
 Female 240 (27.8) 122 (34.7) 118 (23.0)
Age,years [M (P25-P75)] 37.0 (32.0-47.0) 35.0 (30.0-43.0) 39.0 (33.0-48.0) < 0.001
 Age≥45 years [n (%)] 265 (69.3) 79(22.4) 186 (36.3) < 0.001
 Age<45 years [n (%)] 599 (30.7) 273(77.6) 326 (63.7)
Smoking history [n (%)] 255 (29.5) 81 (23.0) 174 (34.0) < 0.001
Drinking history [n (%)] 221 (25.6) 76 (21.6) 145 (28.3) 0.027
WC, cm [M (P25-P75)] 93.0 (86.0-99.0) 86.0 (79.5-93.0) 96.0 (91.0-102.0) < 0.001
BMI, kg/m2 [M (P25-P75)] 26.49 (24.26-28.73) 24.45 (22.15-26.56) 27.74 (25.85-29.74) < 0.001
SBP, mmHg [M (P25-P75)] 130.0 (120.0-139.0) 125.0 (116.0-135.0) 133.0 (123.0-142.0) < 0.001
DBP, mmHg [M (P25-P75)] 81.0 (72.0-88.0) 77.5 (70.0-85.0) 82.0 (75.0-90.0) < 0.001
ALT, U/L [M (P25-P75)] 28.0 (19.0-42.0) 21.0 (15.0-30.0) 34.0 (24.0-54.0) < 0.001
AST, U/L [M (P25- P75)] 21.0 (18.0-26.0) 19.0 (17.0-23.0) 23.0 (19.0-29.0) < 0.001
TC, mmol/L [M (P25-P75)] 4.61 (4.11-5.25) 4.44 (1.04-5.00) 4.77 (4.17-5.41) < 0.001
TG, mmol/L [M (P25-P75)] 1.47 (0.98-2.19) 1.06 (0.74-1.48) 1.84 (1.28-2.59) < 0.001
HDL-C, mmol/L [M (P25-P75)] 1.23 (1.06-1.42) 1.34 (1.15-1.52) 1.14 (1.01-1.33) < 0.001
LDL-C, mmol/L [M (P25-P75)] 2.72 (2.30-3.26) 2.59 (2.15-3.08) 2.84 (2.39-3.37) < 0.001
FBG, mmol/L [M (P25-P75)] 5.29 (4.98-5.72) 5.15 (4.90-5.43) 5.40 (5.07-5.88) < 0.001
SUA, μmol/L [M (P25-P75)] 357.5 (296.3-418.8) 325.5 (262.3-394.0) 375.5 (314.0-434.0) < 0.001
CMI [M (P25-P75)] 0.68 (0.39-1.13) 0.39 (0.25-0.64) 0.88 (0.61-1.40) < 0.001

Data are presented as median with the interquartile range [M (P25-P75)], or frequency (percentage) [n (%)]. a Comparison of the differences between the two groups calculated by Mann-Whitney U test or chi-square test. MAFLD, metabolic associated fatty liver disease; WC, waist circumference; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FBG, fasting blood glucose; SUA, serum uric acid; CMI, cardiometabolic index.