Table 1.

Description of colorimetric biosensors for detection SARS-CoV-2.

Nanomaterial	Size	Target	Biological recognition element	LOD	Reference
Polymer mPEG-PCL- AuNP	222,1 nm	protein Spike	antibody	0,11 ng/mL	[31]
AuNPs-N	30 nm	IgG, IgM e IgA	protein N-antigen		[32]
MNP (γ Fe2O3)		protein Spike	ACE2 receptor	4,98 ng/mL	[33]
AuNPs-ACE2	7 nm	Protein Spike	ACE2 receptor	1.54×10-4 ng/mL	[34]
SiO2 @Au@QD NBs	∼ 240 nm	Protein Spike	IgG and IgM	1:106 dilution	[35]
f-AuNPs	20 nm	spike, envelope, and membrane	antibody	Ct 7	[36]
NPs core–shell Au@Pt	25 nm	Protein spike S1	polyclonal antibodies	11 ng/mL	[37]
AuNPs	40 nm	Protein N	antibody rabbit IgG	3 ng/mL	[38]
AuNPs	–	Protein N	Antigen	150 ng/mL	[39]
SiO2 @Au/QD	∼200 nm	Protein spike S1	antibody	1 ng/mL	[40]
AuNPs	17,7 nm	ORF1, ORF2, E1, and E2	cDNA	580 nM	[41]
AuNPs	16 nm	Protein Spike	antibody monoclonal (mAb)	48 ng/mL	[42]
AuNPs	–	Gene N	DNA+BoNT / A LC	1 copie/μL	[43]
Fe3O4/Au core-shell	30–80 nm	Protein Spike	anti-spike protein antibodies	1200 PFU/mL	[44]
AuNPs	80–120 nm	Gene N	ssDNA	10 copies/μL	[45]
Not applicated		–	DNA biotinilados	∼1 nM	[46]
Not applicated		Gene N and E	ssDNA	10 copies	[47]