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. 2022 Sep 30;17:243. doi: 10.1186/s13019-022-01997-2

Table 4.

Association between repair vs replacement and mortality within subgroups

N No. of events (%) Model 1 Model 2 Model 3
HR (95% CI) HR (95% CI) HR (95% CI)
Healed Endocarditis
 MVr 34 8 (23.5) Reference Reference Reference
 MVR 14 4 (30.8) 1.47 (0.44–4.89) 0.75 (0.19–2.89) 1.62 (0.46–5.73)
Active Endocarditis
 MVr 51 12 (23.5) Reference Reference Reference
 MVR 84 23 (27.7) 1.10 (0.54–2.21) 1.09 (0.54–2.20) 0.85 (0.41–1.77)
Elective
 MVr 23 1 (4.4) Reference Reference Reference
 MVR 8 2 (25.0) 6.72 (0.61–74.48) 6.70 (0.61–74.09) 6.80 (0.58–79.25)
Non-Elective
 MVr 62 19 (30.7) Reference Reference Reference
 MVR 90 25 (28.4) 0.84 (0.46–1.53) 0.90 (0.48–1.68) 0.63 (0.34–1.18)

Model 1: univariate analysis; Model 2: urgency adjusted in endocarditis subgroups, active endocarditis adjusted in urgency subgroups; Model 3: logistic EuroSCORE adjusted only

MVr mitral valve repair, MVR mitral valve replacement, IE infective endocarditis

P-interaction for endocarditis = 0.859

P-interaction for urgency = 0.122