Table 3.

Recommendations of neurocognitive assessment for PCNSL patients at baseline and follow-up

Cognitive area	Recommended tests [37, 38]	Tests suitable for patients in China	Time (min)
General	MMSE	MMSE	5–10
		MoCA	5–10
Premorbid IQ estimation	Barona index	Wechsler Adult Intelligence Scale	5
Attention/executive	Digits forward and backward span; trail making test (Parts A and B)	Digit span	5
		Trail making test (A, B)	5–10
		Stroop test	5–10
Verbal memory	Hopkins verbal learning test-revised	AVLT-Huashan	10
Word fluency	Not mentioned	BNT	5
		Animal verbal fluency test	1
Motor	Grooved pegboard test	Grooved Pegboard test	15–20
Visuospatial ability	Not mentioned	Clock-drawing test	5
		Rey–Osterrieth complex figure test	15–40
QoL	EORTC-QLQ-C30	EORTC QoL questionnaire	10
	BCM 20	Evaluation of brain function in cancer treatment	10–15

There were two systematic reviews identifying cognitive domains and tests to be assessed for PCNSL. One was conducted by Correa et al. [38], and the other was by van der Meulen et al. [37]. The evidence evaluation group adopted and combined their results as “Recommended tests.” Time: duration needs to be taken for each test. MMSE: mini-mental state examination. MoCA: Montreal Cognitive Assessment

IQ Intelligence Quotient, AVLT Huashan: Auditory Verbal Learning Tests—Huashan version, BNT Boston naming test, QoL quality of life