Fig. 1.

Altered gastric microbiota in 16 distal gastric cancer tissues, 13 proximal gastric cancer tissues compared with matched non-tumor tissues. A, B The observed species and Shannon indices were used to evaluate the microbial diversity of the proximal gastric cancer tissues, distal gastric cancer tissues and matched non-tumor tissues. C PCoA of weighted UniFrac distance demonstrated that the proximal, distal tumor tissues and matched non-tumor tissues showed four distinct clusters. D, E The microbial relative abundance of proximal, distal tumor tissues and matched non-tumor tissues at the phylum and genus levels. Proximal T,proximal GC tumor tissues; Proximal N,proximal GC non-tumor tissues; Distal T, distal GC tumor tissues; Distal N, distal GC non-tumor tissues