Table 3.
Association of XPO1 expression with the clinicopathological characteristics of GBC
| Characteristic | Cases | XPO1 expression | P-value | |
|---|---|---|---|---|
| Low | High | |||
| Sex | 0.974 | |||
| Male | 16 | 5 | 11 | |
| Female | 41 | 13 | 28 | |
| Age (years) | 0.423 | |||
| < 60 | 15 | 6 | 9 | |
| ≥ 60 | 42 | 12 | 30 | |
| Histology | 0.407 | |||
| Moderate/WelI | 45 | 13 | 32 | |
| Poor | 12 | 5 | 7 | |
| T class | < 0.001 | |||
| Tis/T1/T2 | 19 | 13 | 4 | |
| T3/T4 | 38 | 5 | 35 | |
| Lymph node metastasis | 0.048 | |||
| Present | 21 | 13 | 11 | |
| Absent | 36 | 5 | 28 | |
| Metastasis | 0.081 | |||
| Negative | 51 | 18 | 33 | |
| Positive | 6 | 0 | 6 | |
| TNM | 0.001 | |||
| I ~ II | 13 | 9 | 4 | |
| III ~ IV | 44 | 9 | 15 | |
Pearson’s χ2 test was applied to detect the correlation between XPO1 expression and clinicopathologic data