Table 2.
Total counts of NADPH oxidise (NOX) enzymes identified from genome sequences of 19 metazoan species. Main numbers indicate the total number of unique sequences identified, including isoforms, splice variants and fragmented gene sequences. Superscript numbers indicate the number of additional identical protein sequences (exact sequence variants)
| Species | Phylum | Totala | NOX1 | NOX2 | NOX3 | NOX4 | NOX5# | Duox |
|---|---|---|---|---|---|---|---|---|
| Amphimedon queenslandica | Porifera | 6 | 1 | 3 (1) | 1 | |||
| Xestospongia bergquistia | Porifera | 3 | 1 | (1) | 1 | |||
| Tethya wilhelma | Porifera | 4 | 2 (1) | 1 | ||||
| Ephydatia muelleri | Porifera | 5 | 1 | (1) | 3 | |||
| Oscarella carmela | Porifera | 4 | 1 | 1 | 2 | |||
| Sycon ciliatum | Porifera | 6 | 2 | 4 | ||||
| Mnemiopsis leidyi | Ctenophora | 1 | 1 | |||||
| Nematostella vectensis | Cnidaria | 3 | 2 | 1 | ||||
| Capitella teleta | Annelida | 5 | 1 | 2 | 2 | |||
| Lingula anatina | Brachipoda | 12 | 1 | 1 | 6 | 4 | ||
| Drosophila melanogaster | Arthropoda | 2 | 1 | 1 | ||||
| Caenorhabditis elegans | Nematoda | 2 | 2 | |||||
| Strongylocentrotus purpuratus | Echinodermata | 6 | 1 | 1 | 3 | 1 | ||
| Acanthaster planci | Echinodermata | 8 | 1 | 6 | 1 | |||
| Branchiostoma floridae | Chordata | 6 | 1 | 1 | 1 | 3 | ||
| Ciona intestinalis | Chordata | 8 | 2 | 1 | 5 | |||
| Danio rerio | Chordata | 7 | 1 | 1 | 1 | 1 | 3 | |
| Xenopus tropicalis | Chordata | 9 | 1 | 11 | 3 | 1 | 2 | |
| Homo sapiens | Chordata | 25 | 3 | 1 | 1 | 72 | 6 | 41 |
aTotal numbers include gene duplications and fragmented genes
#Presence of DspNOX is included in count for column NOX5 within parenthesis