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. 2022 Sep 30;13:487. doi: 10.1186/s13287-022-03116-3

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — miR-146a-5p-modified exosomes promoted the functional recovery of rats with SCI. a BBB scores of rats in three groups on the 1st, 3rd, 5th, 7th, 14th, 21st, 28th dpi (n = 10/group). b Representative footprints of rats walking in 28th dpi in each group and quantification of the footprints analysis. c, d Quantitative analysis and representative MRI images of the lesion area of rats in each group at 28th dpi. Scale bar = 5 mm e Representative immunostaining images of MAP2 (green) /GFAP (red) in spinal cord tissue of each group at 28th dpi. Scale bar = 500 μm. f Representative images of the lesion size (HE staining) in the three groups of rats at 28th dpi. Scale bar = 1000 μm Data above are represented as mean ± SD. *, p < 0.05; **, p < 0.01