Table 3.
The Cox proportional hazard model of the coagulation disorder score for predicting short-term all-cause mortality in critically ill patients with CHF.
| 30-day all-cause mortality | 90-day all-cause mortality | Hospital all-cause mortality | ||||
|---|---|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | HR (95%CI) | p-value | |
| Crude | ||||||
| Coagulation disorder score = 0 | 1 (ref) | 1 (ref) | 1 (ref) | |||
| Coagulation disorder score = 1 or 2 | 1.41 (1.19, 1.67) | <0.001 | 1.29 (1.13, 1.48) | 0.0003 | 1.23 (1.01, 1.48) | 0.0377 |
| Coagulation disorder score = 3 or 4 | 1.96 (1.65, 2.34) | <0.001 | 1.76 (1.53, 2.02) | <0.001 | 1.69 (1.39, 2.05) | <0.001 |
| Coagulation disorder score = 5 or 6 | 3.00 (2.33, 3.86) | <0.001 | 2.65 (2.14, 3.28) | <0.001 | 2.38 (1.82, 3.12) | <0.001 |
| Model I | ||||||
| Coagulation disorder score = 0 | 1 (ref) | 1 (ref) | 1 (ref) | |||
| Coagulation disorder score = 1 or 2 | 1.36 (1.15, 1.62) | 0.0004 | 1.25 (1.09, 1.43) | 0.0018 | 1.21 (1.00, 1.47) | 0.0487 |
| Coagulation disorder score = 3 or 4 | 1.91 (1.60, 2.27) | <0.001 | 1.69 (1.47, 1.95) | <0.001 | 1.68 (1.39, 2.05) | <0.001 |
| Coagulation disorder score = 5 or 6 | 3.12 (2.42, 4.02) | <0.001 | 2.71 (2.19, 3.36) | <0.001 | 2.79 (2.13, 3.66) | <0.001 |
| Model II | ||||||
| Coagulation disorder score = 0 | 1 (ref) | 1 (ref) | 1 (ref) | |||
| Coagulation disorder score = 1 or 2 | 1.38 (1.16, 1.64) | 0.0003 | 1.26 (1.09, 1.45) | 0.0013 | 1.23 (1.01, 1.50) | 0.0360 |
| Coagulation disorder score = 3 or 4 | 1.68 (1.40, 2.01) | <0.001 | 1.53 (1.32, 1.78) | <0.001 | 1.51 (1.23, 1.85) | <0.001 |
| Coagulation disorder score = 5 or 6 | 1.98 (1.50, 2.62) | <0.001 | 1.88 (1.49, 2.37) | <0.001 | 1.93 (1.42, 2.61) | <0.001 |
Crude model was adjusted for none.
Model I was adjusted for age, gender, and ethnicity.
Model II was adjusted for age, gender, ethnicity, liver disease, atrial fibrillation, malignancy, heart rate, respiratory rate, mean arterial pressure, urine output, weight, white blood cell count, glucose, SOFA, SAPSII, the use of mechanical ventilation, vasopressor, statins, β-blocker, warfarin and heparin, and the transfusion of platelet and fresh frozen plasma.
CHF, congestive heart failure; HR, hazard ratio; CI, confidence interval; SOFA, the sequential organ failure assessment; SAPSII, the simplified acute physiology score II.