TABLE 1.
Univariate and multivariate Cox regression analysis determined the independent prognostic performance of our risk score.
| Univariate | HR | HR.95L | HR.95H | p value | Multivariate | HR | HR.95L | HR.95H | p value |
|---|---|---|---|---|---|---|---|---|---|
| a Type | 0.720494516 | 0.561649 | 0.924265 | 0.009888 | a Type | 0.777666 | 0.597662 | 1.011884 | 0.061204 |
| b Gender | 0.912138 | 0.594411 | 1.399697 | 0.673813 | b Gender | 1.12804 | 0.724577 | 1.756162 | 0.59371 |
| c Age | 4.376072 | 2.722401 | 7.034235 | 1.09E-09 | c Age | 3.47046 | 2.061005 | 5.843794 | 2.87E-06 |
| d Cancer_status | 39.2837 | 5.466809 | 282.2869 | 0.000264 | d Cancer_status | 33.08822 | 4.589435 | 238.5545 | 0.000517 |
| e Grade | 3.694602 | 2.280463 | 5.985662 | 1.10E-07 | e Grade | 2.007173 | 1.136654 | 3.54439 | 0.01633 |
| f RiskScore | 1.062957 | 1.048184 | 1.077939 | 1.23E-17 | f RiskScore | 1.036923 | 1.02053 | 1.053579 | 8.21E-06 |
a
Type: Astrocytoma, Oligoastrocytoma, Oligodendroglioma.
b
Gender: Female, Male.
c
Age: ≤41, >41.
d
Cancer_status: Tumor free, With tumor.
e
Grade: G2, G3.
f
RiskScore: risk score = 5.68460388028422 * ZBP1 + 5.58839133632066 * PLK1 + 6.382784047 * CFLAR + 3.560828639 * SQSTM1 + 3.541878806 * FADD.