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Figure 11.

Figure 11.

Recognition receptors CED1 and CED7 in nematodes. CED7 is important in both the dying and the engulfing cells, whereas CED1 is important in the engulfing cell. CED1 can bind to a bridging molecule, TTR-52, which recognizes phosphatidylserine and is required for clearance of dying cells. There is at least one additional receptor (not illustrated) involved in recognition and engulfment of dying cells.