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LC3-associated phagocytosis occurs on engulfment of dying cells. As the phagosome forms, an unknown signal is generated that recruits a complex containing beclin-1 and the phosphoinositide 3-kinase VPS34, and other molecules distinct from those involved in autophagy. As a result, the ligase complex is recruited and LC3 is conjugated to lipids in the phagosome membrane. This facilitates fusion with lysosomes and the degradation of the corpse.
