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Figure 25.

Figure 25.

LC3-associated phagocytosis occurs on engulfment of dying cells. Macrophages expressing an LC3 fused to green-fluorescent protein (GFP) were cocultured with cells (stained red) that were dying by means of different mechanisms. Note the ring of green LC3 around the corpse-containing phagosomes. (Provided by Jennifer Martinez and Clifford Guy, Department of Immunology, St. Jude Children's Research Hospital.)