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. 2022 Sep 30;611(7934):115–123. doi: 10.1038/s41586-022-05165-3

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© The Author(s) 2022, corrected publication 2022

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Extended Data Fig. 3 — The scatter plot shows the number of loci identified with incremental increase in sample size and population diversity. The diagonal line reflects the increase in number of genome-wide significant loci with increasing sample size of European ancestry only. The increase in number of loci departs from this line when adding non-European ancestry samples; EUR: European; EAS: East Asian; AFR: African; HIS: Hispanic; SAS: South Asian; BBJ: Biobank Japan; CKB: China Kadoorie Biobank. Strat0_EUR: N = 22,634 stroke cases (European population-based longitudinal cohorts); Strat1_Strat0&EUR: N = 26,253 stroke cases, adding Spanish and Estonian samples; Strat2_Strat1&EUR: N = 32,980 stroke cases, adding German and Dutch samples; Strat3_Strat2&EUR: N = 42,783, adding large European biobanks; Strat4_Strat3&EUR: N = 73,652 stroke cases, adding MEGASTROKE European; Strat5_Strat4&EAS: N = 91,303 stroke cases, adding Japanese BBJ; Strat6_Strat5&EAS: N = 99,661 stroke cases, adding Chinese CKB; Strat7_Strat6&EAS: N = 101,065 stroke cases, adding other East Asian samples; Strat8_Strat7&AFR: N = 105,026 stroke cases, adding African ancestry samples; Strat9_Strat8&HIS: N = 106,542 stroke cases, adding South American ancestry samples; Strat10_Strat9&SAS, N = 110,182 stroke cases, adding South Asian ancestry samples.