Degradation pathway of CAR in Pseudomonas sp. strain CA10. Enzyme designations: CarAaAcAd, carbazole 1,9a-dioxygenase; CarBaBb, 2′-aminobiphenyl-2,3-diol 1,2-dioxygenase; CarC, 2-hydroxy-6-oxo-6-(2′-aminophenyl)-hexa-2,4-dienoic acid (meta-cleavage compound) hydrolase; CarD, 2-hydroxypenta-2,4-dienoate hydratase; CarE, 4-hydroxy-2-oxovalerate aldolase; CarF, acetaldehyde dehydrogenase (acylating); AntABC, anthranilate 1,2-dioxygenase; CatA, catechol 1,2-dioxygenase; CatB, cis,cis-muconate lactonizing enzyme; CatC, muconolactone δ-isomerase. Compounds: I, CAR; II, 2′-aminobiphenyl-2,3-diol; III, 2-hydroxy-6-oxo-6-(2′-aminophenyl)-hexa-2,4-dienoic acid (meta-cleavage compound); IV, anthranilic acid; V, catechol; VI, cis,cis-muconic acid; VII, muconolactone; VIII, β-ketoadipic acid enol-lactone; IX, 2-hydroxypenta-2,4-dienoic acid; X, 4-hydroxy-2-oxovaleric acid; XI, pyruvic acid; XII, acetaldehyde; XIII, acetyl coenzyme A.