The effect of butyrate on intestinal injury. Control: Control group, SAP: SAP group, SAP + butyrate: SAP + butyrate group. (A) Butyrate markedly improved pathological inflammatory cell infiltration in the ileum. Paraffin sections of ileum tissues were stained with H&E. (B) Histopathologic socres of ileum in each group. Control group versus SAP group: P < .001, Control group versus SAP + butyrate group: P < .001, SAP group versus SAP + butyrate group: P < .05. (C) Butyrate markedly improved pathological inflammatory cell infiltration in the colon. Paraffin sections of colon tissues were stained with H&E. (D) Histopathologic socres of colon in each group. Control group versus SAP group: P < .001, Control group versus SAP + butyrate group: P < .001, SAP group versus SAP + butyrate group: P < .05. n = 8 in each group. SAP, severe acute pancreatitis; H&E, hematoxylin and eosin.