The effect of butyrate on the percentage of CD4 + CD25 + Foxp3 + Treg cells in the lamina propria. Control: Control group, SAP: SAP group, SAP + butyrate: SAP + butyrate group. (A) The percentages of CD4 + CD25 + Foxp3 + Treg cells detected by flow cytometry analysis. (B) Quantification of the percentages of CD4 + CD25 + Foxp3 + Treg cells in each group. Control group versus SAP group: P < .001, Control group versus SAP + butyrate group: P < .01, SAP group versus SAP + butyrate group: P < .01. n = 8 in each group. SAP, severe acute pancreatitis.