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. Author manuscript; available in PMC: 2022 Sep 30.
Published in final edited form as: Science. 2022 Jun 16;376(6599):1313–1316. doi: 10.1126/science.abo3851

Fig. 4. Model of nucleosome retention.

Fig. 4.

Model depicting Pol II transcription through a nucleosome. After Pol II has transcribed sufficiently into the nucleosome, the DNA rewraps. Further transcription may result in a complete transfer of the nucleosome to upstream DNA. The transfer may result in a positional shift of the nucleosome. Pol II is shown as an outline. Metal A is indicated as a magenta sphere. Histone octamer is shown as a gray circle. Nucleosomal entry base pair (bp +1) is indicated with a black arrow. Dyad axis is indicated as a dotted line.