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. 2001 Jun;183(12):3689–3703. doi: 10.1128/JB.183.12.3689-3703.2001

FIG. 4.

FIG. 4

Phthalate catabolic pathway in A. keyseri 12B. Enzymes: PehA, phthalate ester hydrolase (esterase); PhtA, phthalate 3,4-dioxygenase; PhtB, cis-3,4-dihydroxy-3,4-dihydrophthalate dehydrogenase; PhtC, 3,4-dihydroxyphthalate 2-decarboxylase; PcmA, protocatechuate 4,5-dioxygenase; PcmB, 2-hydroxy-4-carboxymuconic semialdehyde dehydrogenase; PcmC, 2-pyrone-4,6-dicarboxylate hydrolase; PcmD, 4-oxalomesaconate hydratase; PcmE, 4-oxalocitramalate aldolase. Chemicals: X, phthalate ester; I, o-phthalate; V, cis-3,4-dihydroxy-3,4-dihydrophthalate; VI, 3,4-dihydroxyphthalate; IV, protocatechuate; XI, 2-hydroxy-4-carboxymuconic semialdehyde; XII, 2-hydroxy-4-carboxymuconic semialdehyde-hemiacetal; XIII, 2-pyrone-4,6-dicarboxylate; XIV, 4-oxalomesaconate; XV, 4-oxalocitramalate; XVI, oxaloacetate; and XVII, pyruvate.