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. 2022 Sep 30;17(9):e0275135. doi: 10.1371/journal.pone.0275135

Table 4. Factors associated with seasonal influenza non-vaccination among Canadian residents aged 46–64 years with at least one chronic medical condition (CMC) (N = 11,250).

Proportion Unvaccinated among Each Response Category (95% CI) Model 1a N = 10,551 Model 2a N = 10,522 Model 3a N = 10,502
aOR (95% CI) aOR (95% CI) aOR (95% CI)
Age (years)
    55–64 0.48 (0.47, 0.49) Ref Ref Ref
    46–54 0.57 (0.55, 0.59) 1.44 (1.31, 1.58) 1.43 (1.30, 1.57) 1.37 (1.25, 1.51)
Province of Residence
    Ontario 0.46 (0.44, 0.48) Ref Ref Ref
    Newfoundland 0.54 (0.50, 0.57) 1.34 (1.13, 1.58) 1.39 (1.17, 1.64) 1.39 (1.17, 1.65)
    Prince Edward Island 0.46 (0.39, 0.54) 0.83 (0.60, 1.14) 0.80 (0.58, 1.11) 0.80 (0.58, 1.11)
    Nova Scotia 0.35 (0.32, 0.38) 0.56 (0.47, 0.66) 0.57 (0.48, 0.67) 0.57 (0.48, 0.68)
    New Brunswick 0.49 (0.43, 0.55) 1.03 (0.79, 1.33) 1.05 (0.80, 1.36) 1.09 (0.84, 1.43)
    Quebec 0.67 (0.65, 0.69) 2.27 (2.00, 2.58) 2.23 (1.96, 2.53) 2.21 (1.95, 2.51)
    Manitoba 0.49 (0.46, 0.52) 1.08 (0.93, 1.27) 1.09 (0.93, 1.27) 1.09 (0.93, 1.28)
    Saskatchewan 0.50 (0.44, 0.56) 1.13 (0.86, 1.49) 1.13 (0.85, 1.50) 1.13 (0.85, 1.50)
    Alberta 0.43 (0.40, 0.46) 0.84 (0.72, 0.97) 0.84 (0.72, 0.97) 0.84 (0.72, 0.97)
    British Columbia 0.49 (0.47, 0.51) 1.09 (0.96, 1.23) 1.10 (0.97, 1.25) 1.12 (0.99, 1.26)
Sex
    Female 0.49 (0.47, 0.50) Ref Ref Ref
    Male 0.52 (0.51, 0.54) 1.22 (1.12, 1.32) 1.20 (1.10, 1.30) 1.18 (1.09, 1.28)
Urbanicity
    Urban 0.49 (0.48, 0.50) Ref Ref Ref
    Rural 0.56 (0.54, 0.58) 1.30 (1.16, 1.47) 1.28 (1.13, 1.44) 1.30 (1.15, 1.46)
Household Income (Canadian dollars)
    < 20000 0.52 (0.47, 0.56) Ref Ref Ref
    ≥20000-<50000 0.54 (0.52, 0.57) 1.02 (0.83, 1.26) 1.00 (0.81, 1.24) 1.00 (0.81, 1.25)
    ≥50000-<100000 0.51 (0.50, 0.53) 0.90 (0.73, 1.09) 0.87 (0.71, 1.07) 0.88 (0.71, 1.08)
    ≥100000-<150000 0.51 (0.49, 0.53) 0.92 (0.75, 1.13) 0.90 (0.73, 1.11) 0.90 (0.71, 1.12)
    ≥150000 0.46 (0.44, 0.48) 0.71 (0.58, 0.88) 0.70 (0.56, 0.86) 0.69 (0.55, 0.87)
Education
    Less than secondary school graduation 0.58 (0.53, 0.62) Ref Ref Ref
    Secondary school graduation, no post-secondary education 0.53 (0.50, 0.56) 0.89 (0.69, 1.14) 0.89 (0.69, 1.14) 0.88 (0.68, 1.13)
    Some post-secondary education 0.49 (0.46, 0.53) 0.87 (0.67, 1.13) 0.88 (0.68, 1.15) 0.87 (0.67, 1.13)
    Post-secondary degree/diploma 0.50 (0.49, 0.51) 0.77 (0.62, 0.96) 0.88 (0.62, 0.98) 0.78 (0.62, 0.98)
Race
    White 0.50 (0.49, 0.51) Ref Ref Ref
    Non-White 0.53 (0.49, 0.56) 1.16 (0.98, 1.38) 1.16 (0.98, 1.38) 1.15 (0.96, 1.36)
CMC by Type
    Heart Disease 0.47 (0.44, 0.50) 0.77 (0.68, 0.89) 0.90 (0.77, 1.04) 0.91 (0.78, 1.06)
    Respiratory Disorders 0.45 (0.42, 0.48) 0.76 (0.66, 0.88) 0.87 (0.74, 1.02) 0.84 (0.72, 0.99)
    Kidney Disease or Failure 0.49 (0.45, 0.54) 0.79 (0.65, 0.98) 0.91 (0.73, 1.12) 0.92 (0.74, 1.14)
    Asthma 0.47 (0.45, 0.48) 0.69 (0.63, 0.76) 0.80 (0.70, 0.90) 0.81 (0.71, 0.92)
    Diabetes 0.48 (0.46, 0.49) 0.79 (0.72, 0.87) 0.91 (0.80, 1.03) 0.93 (0.82, 1.05)
    Cancer 0.48 (0.46, 0.50) 0.82 (0.73, 0.91) 0.98 (0.85, 1.12) 0.98 (0.86, 1.13)
    Other CMC 0.49 (0.48, 0.50) 0.74 (0.67, 0.80) 0.86 (0.76, 0.98) 0.87 (0.77, 0.99)
Number of CMC
    ≥ 2 0.44 (0.43, 0.46) Ref Ref
    1 0.55 (0.53, 0.56) 1.21 (1.04, 1.42) 1.23 (1.05, 1.43)
Care or Assistance Received by Type
    Professional 0.42 (0.38, 0.47) 0.79 (0.64, 0.96) 0.81 (0.66, 0.99)
    Non-Professional 0.45 (0.43, 0.48) 0.92 (0.81, 1.04) 0.93 (0.82, 1.06)
Healthcare Utilization by Type
    Family Doctor Contact 0.49 (0.48, 0.50) 0.53 (0.45, 0.62) 0.53 (0.45, 0.62)
    Specialist Contact 0.47 (0.46, 0.48) 0.77 (0.70, 0.84) 0.78 (0.72, 0.85)
    Hospitalization History 0.48 (0.45, 0.51) 1.11 (0.95, 1.30) 1.12 (0.96, 1.31)
Self-Rated Health
    Excellent 0.51 (0.49, 0.54) Ref
    Very Good 0.52 (0.50, 0.53) 1.06 (0.93, 1.20)
    Good 0.51 (0.49, 0.52) 1.03 (0.89, 1.18)
    Fair 0.46 (0.43, 0.49) 0.92 (0.77, 1.10)
    Poor 0.43 (0.37, 0.48) 0.80 (0.60, 1.07)
Number in Household
    0 0.51 (0.49, 0.54) Ref
    1 0.48 (0.47, 0.50) 0.95 (0.84, 1.08)
    ≥ 2 0.53 (0.51, 0.55) 1.13 (0.98, 1.29)
Exercise
    None or Seldom 0.51 (0.50, 0.52) Ref
    Sometimes or Often 0.49 (0.48, 0.51) 0.95 (0.86, 1.04)
Current Smoking
    Not at All 0.49 (0.48, 0.50) Ref
    Occasionally 0.59 (0.52, 0.65) 1.22 (0.92, 1.63)
    Daily 0.61 (0.57, 0.64) 1.56 (1.33, 1.83)
Alcohol
    Never 0.49 (0.46, 0.51) Ref
    Occasionally 0.47 (0.45, 0.50) 0.94 (0.80, 1.11)
    Regular 0.51 (0.50, 0.52) 1.07 (0.93, 1.22)

aGrey cells indicate variables that were not included in the model represented by that column.