Table 1.
Clinical characteristics of the lung adenocarcinoma patients (TCGA).
| Characteristic | Low expression of CLIC1 | High expression of CLIC1 | P |
|---|---|---|---|
| n | 267 | 268 | |
| T stage, n (%) | .097 | ||
| T1 | 96 (18%) | 79 (14.8%) | |
| T2 | 139 (26.1%) | 150 (28.2%) | |
| T3 | 24 (4.5%) | 25 (4.7%) | |
| T4 | 5 (0.9%) | 14 (2.6%) | |
| N stage, n (%) | .006* | ||
| N0 | 188 (36.2%) | 160 (30.8%) | |
| N1 | 36 (6.9%) | 59 (11.4%) | |
| N2 | 29 (5.6%) | 45 (8.7%) | |
| N3 | 1 (0.2%) | 1 (0.2%) | |
| M stage, n (%) | .729 | ||
| M0 | 165 (42.7%) | 196 (50.8%) | |
| M1 | 10 (2.6%) | 15 (3.9%) | |
| Pathologic stage, n (%) | .036* | ||
| Stage I | 163 (30.9%) | 131 (24.9%) | |
| Stage II | 55 (10.4%) | 68 (12.9%) | |
| Stage III | 34 (6.5%) | 50 (9.5%) | |
| Stage IV | 11 (2.1%) | 15 (2.8%) | |
| Gender, n (%) | .575 | ||
| Female | 139 (26%) | 147 (27.5%) | |
| Male | 128 (23.9%) | 121 (22.6%) | |
| Age, n (%) | .658 | ||
| ≤65 | 132 (25.6%) | 123 (23.8%) | |
| >65 | 129 (25%) | 132 (25.6%) | |
| Smoker, n (%) | .901 | ||
| No | 39 (7.5%) | 36 (6.9%) | |
| Yes | 225 (43.2%) | 221 (42.4%) | |
| Anatomic neoplasm subdivision, n (%) | .350 | ||
| Left | 96 (18.5%) | 109 (21%) | |
| Right | 162 (31.2%) | 153 (29.4%) | |
| Anatomic neoplasm subdivision 2, n (%) | .305 | ||
| Central lung | 33 (17.5%) | 29 (15.3%) | |
| Peripheral Lung | 56 (29.6%) | 71 (37.6%) | |
| OS event, n (%) | .026* | ||
| Alive | 184 (34.4%) | 159 (29.7%) | |
| Dead | 83 (15.5%) | 109 (20.4%) |
CLIC1 = Chloride intracellular channel 1, OS = overall survival.
*
p < .05.