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. 2022 Sep 16;12:1009298. doi: 10.3389/fonc.2022.1009298

Table 2.

Baseline clinicopathological characteristics of matched populations.

RATS (N = 97) VATS (N = 97) OL (N = 97) p Value
Age (y), mean ± SD 77.39 ± 2.63 77.12 ± 1.96 77.58 ± 2.51 0.555
Gender, n (%) 0.423
 Male
 Female
60 (61.86%)
37 (38.14%)
61 (62.89%)
36 (37.11%)
68 (70.10%)
29 (29.90%)
Smoking status, n (%) 0.951
 Never
 Former
 Active
42 (43.30%)
17 (17.53%)
38 (39.18%)
44 (45.36%)
16 (16.49%)
37 (38.14%)
39 (40.21%)
16 (16.49%)
42 (42.30%)
BMI (kg/m2), mean ± SD 23.92 ± 3.04 23.91 ± 3.36 23.66 ± 3.05 0.892
DM, n (%) 15 (15.46%) 13 (13.40%) 12 (12.37%) 0.816
CAD, n (%) 10 (10.31%) 12 (12.37%) 12 (12.37%) 0.875
HP, n (%) 38 (39.18%) 40 (41.23%) 37 (38.14%) 0.904
COPD, n (%) 8 (8.25%) 7 (7.22%) 7 (7.22%) 0.952
FEV1 (% of predicted), mean ± SD 88.85 ± 18.69 89.48 ± 14.77 88.17 ± 17.36 0.876
DLCO (% of predicted), mean ± SD 88.94 ± 18.32 89.81 ± 15.47 88.68 ± 17.28 0.803
History of malignancy, n (%) 2 (2.06%) 3 (3.09%) 3 (3.09%) 1.000
Tumor location, n (%) 0.959
 Right upper lobe
 Right middle lobe
 Right lower lobe
 Left upper lobe
 Left lower lobe
36 (37.11%)
16 (16.49%)
15 (15.46%)
10 (10.31%)
20 (20.62%)
39 (40.21%)
12 (12.37%)
13 (13.40%)
14 (14.43%)
19 (19.59%)
37 (38.14%)
14 (14.43%)
12 (12.37%)
16 (16.49%)
18 (18.56%)
Histology type, n (%) 0.840
 TIS/MIA
 Adenocarcinoma
 Squamous cell
 Mixed/large cell/others
0 (0.00%)
72 (74.23%)
16 (16.49%)
9 (9.28%)
0 (0.00%)
71 (73.20%)
19 (19.59%)
7 (7.22%)
0 (0.00%)
67 (69.07%)
19 (19.59%)
11 (11.34%)
Tumor size (cm), mean ± SD 2.85 ± 1.15 2.75 ± 1.35 2.90 ± 1.26 0.693
Visceral pleural invasion, n (%) 21 (21.65%) 20 (20.62%) 26 (26.80%) 0.548
Pathological T stage, n (%) 0.981
 pTis
 pT1
 pT2
 pT3
 pT4
0 (0.00%)
49 (50.52%)
41 (42.27%)
6 (6.19%)
1 (1.03%)
0 (0.00%)
47 (48.45%)
40 (41.24%)
8 (8.25%)
2 (2.06%)
0 (0.00%)
47 (48.45%)
40 (41.24%)
9 (9.28%)
1 (1.03%)
Pathological N stage, n (%) 0.228
 pN0
 pN1
 pN2
79 (81.44%)
13 (13.40%)
5 (5.15%)
76 (78.35%)
13 (13.40%)
8 (8.25%)
66 (68.04%)
21 (21.65%)
10 (10.31%)
Pathological TNM stage, n (%) 0.707
 0
 IA
 IB
 IIA
 IIB
 IIIA
 IIIB
0 (0.00%)
46 (47.42%)
22 (22.68%)
6 (6.19%)
14 (14.43%)
9 (9.28%)
0 (0.00%)
0 (0.00%)
41 (42.27%)
21 (21.65%)
6 (6.19%)
18 (18.56%)
10 (10.31%)
1 (1.03%)
0 (0.00%)
36 (37.11%)
19 (19.59%)
4 (4.12%)
26 (26.80%)
11 (11.34%)
1 (1.03%)

RATS, robotic-assisted thoracoscopic surgery; VATS, video-assisted thoracoscopic surgery; OL, open lobectomy; SD, standard deviation; BMI, body mass index; DM, diabetes mellitus; CAD, coronary artery disease; HP, hypertension; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; DLCO, diffusing capacity for carbon monoxide; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma.