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. 2022 Apr 5;29(10):1982–1995. doi: 10.1038/s41418-022-00990-5

Fig. 2. PRMT4 overexpression aggravates DIC in vivo.

Fig. 2

AAV-NC or AAV-PRMT4 were applied via tail vein injection and the DIC model was established 14 days later. a Representative images of M-mode echocardiograms; b Representative Masson staining images. c–e Quantitative analysis of LVEF (c, *P < 0.01, #P < 0.01), FS (d, *P < 0.01, #P < 0.01), and LVEDV (e, *P < 0.05, #P < 0.05) by echocardiography; f–h Quantitative analysis of serum CK-MB (f, *P < 0.001, #P < 0.001), AST (g, *P < 0.001, #P < 0.01), and LDH (h, *P < 0.001, #P < 0.01); i Quantitative analysis of fibrosis area. *P < 0.001, #P < 0.01; j Quantitative analysis of TUNEL positive cells by immunofluorescence staining. *P < 0.001, #P < 0.05.