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. 2022 Feb 25;43(10):2624–2635. doi: 10.1038/s41401-022-00885-8

Fig. 7. Schematic illustration of the main findings.

Fig. 7

Dapa directly inhibits saturated fatty acid (PA)-induced MAPK signaling and inflammation, thus attenuating cell apoptosis and fibrosis in cardiomyocytes, which might be associated with the function of NHE1 receptor.