Table 1.
Cardiac echocardiographic parameters and systemic and organ parameters of the experimental mice.
| Parameters | LFD (n = 8) | HFD (n = 8) | HFD + Dapa (n = 8) |
|---|---|---|---|
| EF (%) | 68.88 ± 1.46 | 52.26 ± 1.09* | 63.12 ± 1.93# |
| FS (%) | 38.21 ± 1.20 | 26.57 ± 0.72* | 34.00 ± 1.42# |
| LVIDs (mm) | 2.45 ± 0.04 | 3.08 ± 0.06* | 2.75 ± 0.06# |
| LVIDd (mm) | 3.97 ± 0.09 | 4.20 ± 0.10* | 4.18 ± 0.10ns |
| PWTd (mm) | 0.73 ± 0.03 | 0.86 ± 0.05* | 0.78 ± 0.01ns |
| AWTd (mm) | 0.99 ± 0.04 | 1.22 ± 0.04* | 1.07 ± 0.05# |
| Weight (g) | 26.8 ± 0.66 | 48.3 ± 3.44* | 37.3 ± 3.55# |
| HW/TL (mg/mm) | 6.49 ± 0.51 | 8.33 ± 0.71* | 7.29 ± 0.82# |
| CK-MB (U/L) | 165.48 ± 33.79 | 273.37 ± 40.73* | 211.66 ± 49.59# |
| BNP (ng/L) | 111.59 ± 23.36 | 291.8 ± 20.52* | 142.55 ± 26.86# |
*P < 0.05, compared with LFD mice; #P < 0.05, nsP > 0.05, compared with HFD mice.