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. 2022 Sep 30;12:16415. doi: 10.1038/s41598-022-20186-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Jurkat cells derived exosomes uptake by fibroblasts. Jurkat cells derived exosomes were labeled using FM 1–43 membrane dye. Fibroblasts were treated with several exosome concentrations for 24 h. Exosomal uptake was determined using FACS analysis. X axis: percent of fibroblasts labeled with FM 1–43. (A) Control fibroblasts. (B) Fibroblasts treated with 10¹¹ exosomes. (C) Fibroblasts treated with 10¹² exosomes. Represented images are shown. (D) Quantification of exosomal uptake. The graphs values represent mean (%) ± S.E of three independent experiments. * indicates PV < 0.05.