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. 2022 Sep 12;39(11):5176–5190. doi: 10.1007/s12325-022-02289-w

Table 1.

Demographic and baseline clinical characteristics of survey respondents

Demographic and clinical characteristics Totala
N = 17,071
Monthly headache days categoryb p valuesc
0–3
n = 11,498
≥ 4
n = 5573
Age, years, mean (SD) 40.7 (13.0) 40.3 (13.0) 41.7 (12.9) < 0.001d
Female 11,354 (66.5) 7325 (63.7) 4029 (72.3) < 0.001e
At least some college education 11,891 (69.7) 8119 (70.6) 3772 (67.7) < 0.001f
Employment status < 0.001f
 Employed full time 9557 (56.0) 6614 (57.5) 2943 (52.8)
 Employed part time 2826 (16.6) 1848 (16.1) 978 (17.6)
Household income ≥ ¥5M 8131 (47.6) 5573 (48.5) 2558 (45.9) 0.0023f
Current smoking habit 3783 (22.2) 2435 (21.2) 1348 (24.2) < 0.001g
BMI (kg/m2), mean (SD) 21.86 (3.87) 21.85 (3.76) 21.88 (4.08) 0.7006d
Pain severity score (min–max: 0–10), mean (SD) 5.1 (2.2) 4.8 (2.2) 5.8 (1.9) < 0.001d
ASC-12, mean (SD) 3.4 (3.6) 3.2 (3.6) 3.8 (3.8) < 0.001d
ASC-12 category < 0.001f
 None (0–2) 9011 (52.8) 6362 (55.3) 2649 (47.5)
 Mild (3–5) 4288 (25.1) 2787 (24.2) 1501 (26.9)
 Moderate (6–8) 2113 (12.4) 1326 (11.5) 787 (14.1)
 Severe (≥ 9) 1659 (9.7) 1023 (8.9) 636 (11.4)

Data are n (%), unless otherwise indicated

ASC-12 Allodynia Symptom Checklist, BMI body mass index, M million, max maximum, min minimum, SD standard deviation

aData in the total column previously reported [3] are age, sex, employment status, and pain severity

bData in the 0–3 monthly headache days column previously reported [4] are age, sex, total employed, pain severity, and total current use of acute treatment. Data for ≥ 4 monthly headache days as a single category have not been previously reported

cPairwise comparisons between migraine headache days categories (0–3 vs. ≥ 4); note that the large sample size may result in statistically significant differences of minimal clinical importance

dt test (continuous variable)

eChi-square test, female versus male

fChi-square test across all categories (education categories: less than high school, high school graduate, college or technical school, university graduate, post-graduate qualification, not sure, or prefer not to answer; employment categories: employed full time, employed part time, homemaker, retired, student, disability payment, not employed and looking for work, not employed and not looking for work, or prefer not to answer; household income categories: < ¥1,000,000, ¥1,000,000–¥2,999,999, ¥3,000,000–¥7,999,999, ¥8,000,000–¥9,999,999, > ¥10,000,000, or prefer not to answer)

gChi-square test, current smoker versus current non-smoker