Why carry out this study?

Unmet needs for acute treatment of migraine in Japan, particularly for people with cardiovascular disease (CVD) or cardiovascular risk factors (CVRFs), are not currently well understood.

The OVERCOME (Japan) observational study assessed diagnosis, symptomatology, treatment, and impact of migraine in a representative sample of the Japanese population.

Survey results reported here include the types of acute medications used, patient-reported medication effectiveness, and CVD and/or CVRFs in people with migraine in Japan.

What was learned from the study?

Potential unmet needs, such as insufficient effectiveness of current treatments, former triptan use, contraindications to triptans, and/or CVRFs, were reported by nearly three-quarters (74.1%) of people with migraine in Japan.

The impacts of these potential unmet needs may include substantial disability related to migraine and reduced options for acute treatment.

There are substantial opportunities for improving the care of people with migraine in Japan, including prescription of novel acute medications.