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. 2022 Aug 13;96(11):2967–2981. doi: 10.1007/s00204-022-03361-8

Fig. 4.

Fig. 4

Increased hepatotoxicity of OTA in heterozygous albumin knockout mice. A Gross pathology. B Histopathology with hematoxylin and eosin staining; scale bars: 50 µm (untreated and left panel of OTA) and 200 µm (right panel of OTA). C Liver enzyme activities in the blood of untreated and OTA-treated wild-type, heterozygous (albumin ±) and homozygous (albumin −/−) albumin knockout mice. *p value ≤ 0.05, **p value ≤ 0.01 Tukey's multiple comparisons test; n = 5 mice per group