Table 3.
The descriptive data, clinical parameters comparison between responders and non-responders group
| Non-Responders | Responders | Test value | P- value | Sig. | |
|---|---|---|---|---|---|
| No. = 16 | No. = 50 | ||||
| Age | |||||
| Mean ± SD | 62.75 ± 5.05 | 62.52 ± 6.17 | 0.135• | 0.893 | NS |
| Range | 53–69 | 52–74 | |||
| Gender | |||||
| Male | 12 (75.0%) | 26 (52.0%) | 2.625* | 0.105 | NS |
| Female | 4 (25.0%) | 24 (48.0%) | |||
| BMI | |||||
| Mean ± SD | 31.94 ± 4.82 | 30.54 ± 4.46 | 1.069• | 0.289 | NS |
| Range | 26–43 | 24–46 | |||
| Diabetes | |||||
| Yes | 10 (62.5%) | 29 (58.0%) | 0.102* | 0.750 | NS |
| HTN | |||||
| Yes | 9 (56.2%) | 34 (68.0%) | 0.737* | 0.391 | NS |
| CKD | |||||
| eGFR > 60 | 7 (43.8%) | 50 (100%) | 32.602* | < 0.001 | HS |
| eGFR30-60 | 9 (56.2%) | 0 (0.0%) | |||
| Cardiomyopathy | |||||
| DCM | 3 (18.8%) | 31 (62.0%) | 9.078* | 0.003 | HS |
| ICM | 13 (81.2%) | 19 (38.0%) | |||
| ACEI | |||||
| Yes | 7 (43.8%) | 43 (86.0%) | 11.781* | 0.001 | HS |
| ARNI | |||||
| Yes | 0 (0.0%) | 7 (14.0%) | 2.506* | 0.113 | NS |
| BB | |||||
| Yes | 16 (100.0%) | 50 (100.0%) | – | – | – |
| Diuretics | |||||
| Yes | 16 (100.0%) | 47 (94.0%) | 1.006* | 0.316 | NS |
| MRAs | |||||
| Yes | 4 (25.0%) | 40 (80.0%) | 16.500* | < 0.001 | HS |
| SGLT2 inhibitor | |||||
| Yes | 2 (12.5%) | 6 (12.0%) | 0.003* | 0.957 | NS |
| QRS duration (msec) | |||||
| Mean ± SD | 135.00 ± 5.16 | 152.80 ± 24.25 | − 2.901• | 0.005 | HS |
| Range | 130–140 | 130–200 | |||
| Non-Strauss/Strauss | |||||
| Non-Strauss | 10 (62.5%) | 26 (52.0%) | 0.539* | 0.463 | NS |
| Strauss | 6 (37.5%) | 24 (48.0%) | |||
| Range | – | 5–15 |
Body mass index, chronic kidney disease, dilated cardiomyopathy, hypertension, ischemic cardiomyopathy, standard deviation, angiotensin converting enzyme inhibitor, angiotensin receptor neutrilypsin inhibitor, beta-blockers, body mass index, chronic kidney disease, dilated cardiomyopathy, mineralocorticoids receptor antagonists, standard deviation, number. *: Chi-square test; •: Independent t-test