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. 2022 Sep 30;12:16450. doi: 10.1038/s41598-022-20281-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Toxoplasma RH-infected BV2-derived exosomes induce downregulation of anti-tumor associated genes in U87 glioma cells by Toxoplasma RH-infected BV2-derived exosomes. (A) Real-time PCR for FoxO1, PTEN, and PDCD4 expressions in Toxoplasma RH-infected BV2-derived exosomes versus those with PBS exosomes. β-actin mRNA was used as a control. (B) FoxO1 expression was determined by Western blot analysis and the statistical evaluation of densitometry data was performed using the ImageJ program. *P < 0.05 was obtained by Student’s t test.