Figure 5.

(A) 3D structure of L. major mevalonate kinase in complex with docked R-mevalonate (MEV: cyan color) and caprilic acid (CA: purple color). Ligand is shown in ball and stick representation, binding site residues shown in line (non H-bonds interactions residues) and thick sticks (H-bonds interaction residues) representation. Water molecules were shown in red color (thin sticks representation). H-bonds interaction shown via dashed black line. (B,C) Shows 2D interaction diagram of MEV and CA, respectively. Color scheme used in figure is based on types of interactions, shown in figure.