Figure 4.

CPT1A clustering with immune pathways. Visual depiction of the clustering of CPT-1A with signalling pathways and whether the clustering occurs in the context of overexpression (red colour, left) or underexpression (green colour, right). The top left image shows the pathways which cluster with CPT-1A in the primary breast carcinomas. The remaining images show the additional pathways which cluster with CPT-1A in high grade carcinomas (top right), advanced stage or recurrence (bottom left) and in patients with a worse prognosis, as indicated by death by 5 years (bottom right). Where clustering is limited to a particular subgroup of carcinomas (receptor status or histological subtype), this is indicated in brackets beneath the signalling pathway.