Table 2.
Correlation between ACOT2 expression levels in AML and mutated genes.
| Characteristics | Low expression of ACOT2 | High expression of ACOT2 | P |
|---|---|---|---|
| FLT3 mutation, n (%) | 0.259 | ||
| Negative | 47 (32%) | 55 (37.4%) | |
| Positive | 26 (17.7%) | 19 (12.9%) | |
|
| |||
| IDH1 R132 mutation, n (%) | 0.077 | ||
| Negative | 64 (43%) | 72 (48.3%) | |
| Positive | 10 (6.7%) | 3 (2%) | |
|
| |||
| IDH1 R140 mutation, n (%) | 0.782 | ||
| Negative | 68 (45.6%) | 69 (46.3%) | |
| Positive | 7 (4.7%) | 5 (3.4%) | |
|
| |||
| IDH1 R172 mutation, n (%) | 0.497 | ||
| Negative | 73 (49%) | 74 (49.7%) | |
| Positive | 2 (1.3%) | 0 (0%) | |
|
| |||
| RAS mutation, n (%) | 0.276 | ||
| Negative | 69 (46%) | 73 (48.7%) | |
| Positive | 6 (4%) | 2 (1.3%) | |
|
| |||
| NPM1 mutation, n (%) | 0.115 | ||
| Negative | 54 (36%) | 63 (42%) | |
| Positive | 21 (14%) | 12 (8%) | |