Inhibition of ABCC5, CLDH1, and CSTA reduced the carcinogenesis of NSCLC cells. (a) Representative images of EDU staining for Control, siABCC5, siCLDN1, and siCSTA groups. Magnification, ×200. (b) Comparison of colonies number among control, siABCC5, siCLDN1, and siCSTA groups. (c) Representative images of invasive ability comparison among Control, siABCC5, siCLDN1, and siCSTA groups. Magnification, ×100. Data are displayed as the mean ± standard deviation. Student's t-test was performed. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001. NSCLC, non-small-cell lung cancer; EDU, 5-ethynyl-2′-deoxyuridine; ABCC5, ATP-binding cassette subfamily C member 5; CLDN1, Claudin 1; CSTA, Cystatin A.