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Cryptococcus neoformans ATIC crystal structure. Crystal structure of C. neoformans ATIC dimer. Monomer A is colored brown, and monomer B is colored green. The two magenta spheres represent bound magnesium ions. Asterisks in black and orange represent the approximate position of IMP cyclohydrolase and AICAR transformylase active sites, respectively. ATIC, AICAR transformylase/5′-inosine monophosphate cyclohydrolase; IMP, 5'-inosine monophosphate.
