Table 1.

Summary of tested drugs displaying antiaggregation activity toward bovine γ-crystallin-rich proteins exposed to oxidant stress for 24 h and/or thermal stress at 72 °C for 20 min

Compound name	MW (g)	Usage	Properties	Antiaggregation activity	Provenience, appearance
Bixin (drug B)	394.5	Food color	Antineoplastic	Medium heat shock inhibitor	Orange colored solid
Closantel (drug C) Two enantiomers C(R) and C(S)	663.1	Clinical drug	Antihelminthic	Medium strong dual inhibitor	Synthetic, clear solid, colorless
Chaulmoogric acid (drug M)	280.4	Experimental drug	Antibacterial, antileprotic	Dual heat shock inhibitor + antioxidant	Natural product, colorless, oily
Gambogic acid (drug G)	628.7	Experimental drug	Anti-inflammatory, anticancer, multiple actions	Strong heat shock inhibitor	Natural product, yellow solid
Dihydrogambogic (drug D) Acid (reduced G)	630.8	Experimental drug	Undetermined activity	Strong heat shock inhibitor	Modified natural product, solid
Hexachlorophene (drug X)	406.9	Clinical drug	Topical antimicrobial	Medium heat shock inhibitor	Synthetic, solid, colorless