Table 3.

Binding and thermodynamic parameters of HγD interaction with drugs C, G, and M at 25, 30, and 37 °C

Sample	KSV (M−1) (×103)			Kq (M−1 s−1) (×1012)			Kb (M−1) (×105)			ΔG (kcalM−1)
	25 °C	30 °C	37 °C	25 °C	30 °C	37 °C	25 °C	30 °C	37 °C	25 °C	30 °C	37 °C
C	4.215	4.197	4.107	0.739	0.736	0.72	4.7	3.07	1.57	−6.4	−6.2	−5.9
G	10.252	8.440	7.880	1.79	1.47	1.38	6.1	3.9	1.34	−7.9	−7.7	−7.2
M	0.288	0.507	0.680	0.051	0.08	0.012	0.00026	0.00069	0.00070	−1.9	−2.5	−2.6