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. 2022 Aug 28;298(10):102417. doi: 10.1016/j.jbc.2022.102417

Table 4.

Binding and thermodynamic parameters of MγS interaction with drugs C, G, and M at 25, 30, and 37 °C

Sample KSV (M−1) (×103)
Kq (M−1 s−1) (×1012)
Kb (M−1) (×105)
ΔG (kcalM−1)
25 °C 30 °C 37 °C 25 °C 30 °C 37 °C 25 °C 30 °C 37 °C 25 °C 30 °C 37 °C
C 4.828 4.249 2.988 0.847 0.745 0.524 1.38 0.327 0.0726 −7.0 −6.2 −4.1
G 7.283 8.034 4.905 1.37 1.4 0.86 1.37 0.123 0.35 −8.2 −5.6 −6.5
M 0.793 0.733 0.491 0.14 0.13 0.86 0.00093 0.00075 0.00035 −2.7 −2.6 −2.2