Fig. 6.
Correlation between NOX4 and erythrocyte content in atherosclerotic plaques obtained from patients with asymptomatic and symptomatic carotid artery disease. (A) Erythrocytes were stained using a specific antibody against glycophorin C and positive areas were quantified. Data were set in relation to the total plaque area. (A), Data are presented as a scatter dot plot where the horizontal line depicts the median and were compared using the Mann-Whitney-U test. (B–C) Spearman's correlation (rS) between plaque NOX4 expression and erythrocytes in asymptomatic and symptomatic patients. (D) Representative slides for glycophorin C immunohistochemistry in plaques from patients with asymptomatic and symptomatic carotid artery disease. Scale bar upper picture: 2.5 mm. Scale bar lower picture: 300 μm.