Table 2.

Sequences of guide RNAs

Target gene	gRNA	Target sequence
Chga	gRNA1	5′-GCA​TAG​CGA​GCC​GGA​CGG​TG-3′
	gRNA2	5′-TGT​GCG​CCG​GGC​AAG​GTG​AG-3′
	gRNA3	5′-GCG​AGT​CGG​AGA​TGA​CCT​CC-3′
	gRNA4	5′-GTT​GTC​TGC​ATG​AGG​CCA​CG-3′
Chgb	gRNA1	5′-TGG​CGA​GCG​GCA​CCA​TGC​AG-3′
	gRNA2	5′-AAA​CCC​GGT​ACT​TGC​AGC​GC-3′
	gRNA3	5′-TCA​GGA​CTT​GCC​GGC​ACT​CA-3′
	gRNA4	5′-TCA​CTA​GAG​GCT​CGA​ACA​TG-3′