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. 2022 Oct 1;9:38. doi: 10.1186/s40662-022-00307-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Association of age with vessel densities in the DCP stratified by sex. a Whole measure area; b Parafovea; c Temporal; d Superior; e Nasal; f Inferior. The DCP vessel densities in most regions decreased linearly with age in males (blue band). On the other hand, the DCP vessel densities in all regions decreased non-linearly with age and remained stable or slightly declined after 50 years in females (red band). Models were adjusted for sex, education, current smoking status, current drinking status, body mass index, axial length, and signal strength index of optical coherence tomography angiography image. DCP, deep retinal capillary plexus