Table 3.

Regression models for the Ad-HER production

Response	Equations of the responses	Adjusted R2	Lack of fit
Titer (IFU/mL)	9.0 × 1010–1.1 × 1010 × MOI − 6.6 × 109 × TOI − 1.3 × 1010 × pH + 2.0 × 107 × MOI × MOI − 1.8 × 108 × TOI × TOI  + 1.6 × 109 × MOI × pH + 1.3 × 109 × TOI × pH	0.929	0.091
IOR	1874.9–77.1 × MOI-485.3 × TOI − 133.9 × pH + 4.8 × MOI × MOI  + 2.2 × MOI × TOI − 6.9 × MOI × pH + 63.9 × TOI ×  pH	0.976	0.136