Figure 1.

Patient disposition. ^aPatients diagnosed with iCCA (ICD-O-3 code: C221) or eCCA (ICD-O-3 codes: C240, C241,249). ^bCancer of unknown primary (ICD-O-3 code C809) and adenocarcinoma histology codes 8140/2 (adenocarcinoma in situ), 8140/3 (adenocarcinoma not otherwise specified), 8141/3 (scirrhous adenocarcinoma), 8143/3 (superficial spreading adenocarcinoma), and 8147/3 (basal cell adenocarcinoma). Abbreviations: CCA, cholangiocarcinoma; CUP, cancer of unknown primary; eCCA, extrahepatic cholangiocarcinoma; iCCA, intrahepatic cholangiocarcinoma; ICD-O-3, International Classification of Diseases for Oncology.