Table 3.
PE-related features during severe pneumonia in the PE-like group vs the PE and non-PE groups
| Variable | PE like (n=8) | PE (n=7) | Non-PE (n=53) |
|---|---|---|---|
| SBP (mm Hg) | 153 (147.3–160.8)a | 154 (145.0–156.0) | 108 (103.5–119.0) |
| DBP (mm Hg) | 95.5 (90.8–104.5)a | 100.0 (97.0–109.0) | 69.0 (64.5–76.5) |
| Hypertension | 8/8 (100.0)a | 7/7 (100.0) | 0/53 (0) |
| Proteinuria | 6/6 (100.0) | 5/7 (71.4) | 8/14 (57.1) |
| Platelet count per μL | 245 (191.5–328.3) | 197 (137.0–309.0) | 259 (187.0–323.0) |
| Thrombopenia<100,000/μL | 0/8 (0) | 0/7 (0) | 0/51 (0) |
| AST (U/L) | 99 (28.3–160.8) | 104 (42.0–164.0) | 74 (44.0–144.5) |
| ALT (U/L) | 114.5 (32.8–290.3) | 85.0 (39.0–150.0) | 58.8 (35.5–136.5) |
| Transaminitis more than twice the normal values | 5/8 (62.5) | 6/7 (85.7) | 32/52 (62.5) |
| LDH (U/L) | 282 (203.8–360.3) | 497.5 (347.3–538.3) | 280.5 (234–320.5) |
| LDH>600 U/L | 0/8 (0) | 0/7 (0) | 2/52 (3.9) |
| Creatinine (mg/dL) | 0.32 (0.25–0.41)b | 0.49 (0.47–0.64) | 0.35 (0.31–0.44) |
| Creatinine level>1 mg/dL | 0/8 (0) | 0/7 (0) | 0/51 (0) |
| Mean uterine artery PI >95th percentile | 1/5 (20.0) | — | 2/13 (15.4) |
| sFlT-1–to–PlGF ratio | 4.6 (2.6–12.8)b | 122.9 (49.4–225.5) | 6.7 (2.3–10.9) |
Continuous data are presented as median (interquartile range). Categorical data presented as frequency (percentage).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; DBP, diastolic blood pressure; LDH, lactate dehydrogenase; PE, preeclampsia; PI, pulsatility index; PlGF, placental growth factor; SBP, systolic blood pressure; sFlt-1, soluble fms-like tyrosine kinase 1.
a
Statistically significant difference compared to the non-PE group;
b
Statistically significant difference compared to the PE group.
Serrano. Preeclampsia-like syndrome in severe COVID-19. Am J Obstet Gynecol MFM 2022.