Table 4.
PE-related features after severe pneumonia in the PE-like group vs the PE and non-PE groups
| Variables | PE like (n=8) | PE (n=7) | Non-PE (n=53) |
|---|---|---|---|
| SBP (mm Hg) | 115 (112.3–125.8)a,b | 128 (123.0–137.0) | 104 (98.0–112.0) |
| DBP (mm Hg) | 76 (63.8–77.5)a | 83 (81.0–90.0) | 65 (60.0–71.0) |
| Hypertension | 0/8 (0) | 2/7 (28.5) | 1/53 (1.9) |
| Proteinuria | 0/2 (0) | — | 3/9 (33.3) |
| Platelet count per μL | 273,500 (224,800–384,500) | 371,000 (307,000–406,000) | 290,000 (240,000–352,000) |
| Thrombopenia<100,000/μL | 0/8 (0) | 0/7 (0) | 0/51 (0) |
| AST (U/L) | 18 (16–25) | 29 (24–31) | 23 (17–43) |
| ALT (U/L) | 15 (9–33) | 30 (20–45) | 25 (14–37) |
| Transaminitis more than twice the normal values | 1/7 (14.3) | 0/7 (0) | 6/47 (12.8) |
| LDH (U/L) | 223 (167.0–246.3) | 328.5 (239.0–367.8) | 203 (173.0–202.5) |
| LDH>600 U/L | 0/8 (0) | 0/7 (0) | 0/53 (0) |
| Creatinine (mg/dL) | 0.41 (0.39–0.42) | 0.43 (0.38–0.49) | 0.40 (0.34–0.51) |
| Creatinine level>1 mg/dL | 0/8 (0) | 0/7 (0) | 0/53 (0) |
| Mean uterine artery PI >95th percentile | 1/7 (14.3) | — | 4/29 (13.8) |
| sFLT-1–to–PlGF | 11.3 (7.3–23.3) | 15.2 (8.5–21.9) | 5.91 (3.4–10.4) |
Continuous data are presented as median (interquartile range). Categorical data are presented as frequency (percentage).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; DBP, diastolic blood pressure; LDH, lactate dehydrogenase; PE, preeclampsia; PI, pulsatility index; PlGF, placental growth factor; SBP, systolic blood pressure; sFlt-1, soluble fms-like tyrosine kinase 1.
a
Statistically significant difference compared to the PE group;
b
Statistically significant difference compared to the non-PE group.
Serrano. Preeclampsia-like syndrome in severe COVID-19. Am J Obstet Gynecol MFM 2022.