Table 5.
Interaction analysis of the studied SNPs on BD risk.
| rs1261084C/T | rs10774053A/G | rs10466907G/T | rs1625579A/C | BD (%) | Control (%) | OR (95% CI) | P value∗ |
|---|---|---|---|---|---|---|---|
| CT | AG | GT | AC | 7 (2.8) | 11 (5.2) | 1 [reference] | |
| CC | AA | GT | AA | 7 (2.8) | 2 (0.9) | 5.50 (0.88-34.46) | 0.03 |
| CC | AA | GT | AC | 2 (0.8) | 7 (3.3) | 0.45 (0.07-2.81) | 0.36 |
| CC | AG | GT | AC | 5 (2.0) | 8 (3.8) | 0.98 (0.23-4.25) | 0.72 |
| CC | AG | GT | CC | 3 (1.2) | 8 (3.8) | 0.59 (0.11-3.01) | 0.52 |
| CC | GG | GT | AC | 8 (3.2) | 3 (1.4) | 4.19 (0.82-21.40) | 0.08 |
| CT | AA | GG | AC | 4 (1.6) | 5 (2.3) | 1.26 (0.25-6.36) | 0.76 |
| CT | AA | GT | AC | 6 (2.4) | 4 (1.9) | 2.36 (0.49-11.45) | 0.28 |
| CT | AG | GG | AC | 7 (2.8) | 5 (2.3) | 2.20 (0.50-9.75) | 0.28 |
| CT | AG | GT | AA | 11 (4.4) | 8 (3.8) | 2.16 (0.58-8.04) | 0.24 |
| CT | AG | GT | CC | 9 (3.6) | 6 (2.8) | 2.36 (0.58-9.580 | 0.20 |
| CT | GG | GG | AC | 4 (1.6) | 7 (3.3) | 0.90 (0.19-4.24) | 0.88 |
| CT | GG | GT | AA | 7 (2.8) | 2 (0.9) | 5.50 (0.88-34.46) | 0.04 |
| CT | GG | GT | AC | 9 (3.6) | 6 (2.8) | 2.36 (0.58-9.58) | 0.20 |
| TT | AG | GG | AC | 5 (2.0) | 6 (2.8) | 1.31 (0.29-5.98) | 0.72 |
| TT | AG | GT | AA | 10 (4.0) | 3 (1.4) | 5.24 (1.06-25.97) | 0.036 |
| TT | AG | GT | AC | 14 (5.6) | 9 (4.2) | 2.44 (0.69-8.66) | 0.16 |
| TT | AG | GT | CC | 2 (0.8) | 7 (3.3) | 0.45 (0.07-2.81) | 0.36 |
| TT | GG | GT | AC | 11 (4.5) | 3 (1.4) | 5.76 (1.17-25.25) | <0.001 |
OR: odd ratio; CI: confidence interval; BD: bipolar disorder. ∗P values were corrected for multiple testing. ∗P < 0.05 was considered statistically significant.