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. 2022 Sep 19;2022:3498310. doi: 10.1155/2022/3498310

Figure 8.

Figure 8

Effect of Jatrorrhizine on the protein expressions of TLR4, MyD88, p-p65, and COX-2 in DSS-induced UC in mice. (a) Western blotting images of TLR4, MyD88, p-p65, p65, and GAPDH. (b) Relative TLR4 protein expression in colon tissue. (c) Relative MyD88 protein expression in colon tissue. (d) Western blotting images of COX-2 and GAPDH. (e) Relative p-p65/p65 protein expression in colon tissue. (f) Relative COX-2 protein expression in colon tissue. All data were presented as mean ± SD. (Ctrl: control group; DSS: DSS group; 5-ASA: mesalazine group; Jat L: Jatrorrhizine 40 mg/kg dose group; Jat M: Jatrorrhizine 80 mg/kg dose group; Jat H Jatrorrhizine 160 mg/kg dose group; ∗p < 0.05 and ∗∗p < 0.01 vs. control group; #p < 0.05 and ##p < 0.01 vs. DSS group).