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. 2022 Oct 1;8:36. doi: 10.1038/s41540-022-00249-2

Fig. 2. Schematic of stable motif procedure applied to the system of Eq. 6.

Fig. 2

The network structure of the system is depicted in panel a. Circle-tipped arrows represent inhibition, while wedge-tipped arrows represent activation. In panel b, the bounding systems in Eqs. 8 and 9 are depicted alongside the original system. Note that these bounding systems are monotone input/output systems. Panel c illustrates the characteristic feedback method of identifying steady states in monotone input/output systems, wherein the effect of overriding a feedback vertex set (FVS), in this case, the set containing ym or yM, is considered, as described in the example of Eq. 4.